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Thermal Testing in Bone Pain (TiBoP)

NCT02887833 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2021-06-23

No results posted yet for this study

Summary

If cancer spreads to bones it can be very painful, especially when trying to move around. One of the best treatments is radiotherapy, which has to be given in a cancer centre. Even with this treatment, only about half of people will get good pain relief, and that can take up to 6 weeks to work fully. If we know who is unlikely to benefit , then we can explore other forms of pain relief sooner, without having to go through radiotherapy unnecessarily.

We have found that there may be a very simple way to identify patients likely to get good pain relief, using a test of changes in temperature sensation over the painful bone. This study will explore whether this simple bedside test can be used in a community setting to identify which patients suffering from cancer induced bone pain will get good pain relief from radiotherapy.

Conditions

  • Cancer Induced Bone Pain
  • Secondary Malignant Neoplasm of Bone
  • Toxicity Due to Radiotherapy
  • Pain

Interventions

OTHER

Clinical biomarker (thermal sensory testing)

Thermal sensitivity testing: The area of CIBP and a corresponding unaffected (control) area will be assessed using warm and cool thermal rollers (Rolltemp, Somedic, Sweden). The control area will either be the contralateral side, or an area proximal to the affected site.

Sponsors & Collaborators

  • NHS Lothian

    collaborator OTHER_GOV

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Lesley Colvin, PhDFRCA FRCP · NHS Lothian/ University of Edinburgh

  • Marie Fallon, MD FRCP · University of Edinburgh

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-31
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02887833 on ClinicalTrials.gov