Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Summary

This phase II clinical trial studies how well thermal ablation and spine stereotactic radiosurgery work in treating patients with cancer that has spread to the spine (spine metastases) and is at risk for compressing the spinal cord. Thermal ablation uses a laser to heat tumor tissue and helps to shrink the tumor by destroying tumor cells. Stereotactic radiosurgery delivers a large dose of radiation in a short time precisely to the tumor, sparing healthy surrounding tissue. Combining thermal ablation with stereotactic radiosurgery may be a better way to control cancer that has spread to the spine and is at risk for compressing the spinal cord.

Conditions

• Malignant Digestive System Neoplasm
• Metastatic Head and Neck Carcinoma
• Metastatic Kidney Carcinoma
• Metastatic Malignant Neoplasm in the Spine
• Metastatic Malignant Neoplasm of Unknown Primary
• Metastatic Melanoma
• Prostate Carcinoma Metastatic in the Bone
• Sarcoma
• Solid Neoplasm
• Spinal Cord Compression
• Stage IV Breast Cancer AJCC v6 and v7
• Stage IV Lung Non-Small Cell Cancer AJCC v7
• Thyroid Gland Carcinoma

Interventions

PROCEDURE

Computed Tomography

Undergo CT scan

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

RADIATION

Stereotactic Radiosurgery

Undergo CT-guided SSRS

PROCEDURE

Thermal Ablation Therapy

Undergo thermal ablation therapy

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• M.D. Anderson Cancer Center

  lead OTHER

Principal Investigators

• Jing Li · M.D. Anderson Cancer Center

Study Design

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-08-29

Primary Completion

2027-10-28

Completion

2027-10-28

Countries

• United States

Study Locations