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The Study of ELEctronic Cigarette Toxicity in a Human Model in Vivo Model of Inflammation and Vascular Dysfunction

NCT02739438 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-07-05

No results posted yet for this study

Summary

To carry out a prospective cohort study of healthy volunteers, assessing differences between baseline pulmonary inflammation, response to LPS inhalation and endothelial function, as measured by flow mediated dilation between, electronic cigarette uses, cigarette smokers and non smokers.

Conditions

  • Acute Lung Injury

Interventions

OTHER

Electronic cigarette use

Subjects who use electronic cigarettes daily and have not used conventional cigarettes in the previous 3 months.

OTHER

Cigarette use

Subjects who smoke at least ¼ pack cigarettes per day for the past 1 year, with no history of electronic cigarette use in the last 30 days.

OTHER

Control group

Subjects with no history of prior conventional cigarette (\< 100 cigarettes lifetime) or electronic cigarette use.

Sponsors & Collaborators

  • Queen's University, Belfast

    lead OTHER

Principal Investigators

  • Murali Shyamsundar, PhD · Queen's University, Belfast

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02739438 on ClinicalTrials.gov