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Multimodal Imaging Techniques in Assessing the Surgical Risk for Eloquent Arteriovenous Malformations

NCT02868008 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2016-08-16

No results posted yet for this study

Summary

Microsurgical resection for eloquent arteriovenous malformations (AVMs) remains challenging. Currently, there are only two grading systems concerning pretreatment assessment of brain AVMs: the Spetzler-Martin grading system proposed by Spetzler and Martin in 1986 and the supplementary grading system proposed by Lawton in 2010. Controversies exist regarding the treatment timing and treatment modalities for eloquent AVMs. Till now, there is no clinical trial concerning the efficacy of multimodal magnetic resonance imaging techniques in assessing the surgical risk for eloquent AVMs. The investigators assume that multimodal imaging-based grading system is superior to the classic Spetzler-Martin grading system and the supplementary grading system in predicting the surgical risk for eloquent AVMs.

Conditions

  • Intracranial Arteriovenous Malformations

Interventions

PROCEDURE

Microsurgical resection of brain AVMs

fMRI guided microsurgical resection of brain AVMs

Sponsors & Collaborators

  • Chinese PLA General Hospital

    collaborator OTHER

  • Beijing Hospital

    collaborator OTHER_GOV

  • Xuanwu Hospital, Beijing

    collaborator OTHER

  • Beijing Friendship Hospital

    collaborator OTHER

  • Beijing Tiantan Hospital

    lead OTHER

Principal Investigators

  • Shuo Wang, M.D. · Beijing Tiantan Hospital

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
12 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2019-06-30
Completion
2019-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02868008 on ClinicalTrials.gov