Plasma Dipeptidyl-peptidase-4 Activities With No-reflow and Bleeding
NCT02849691 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 747
Last updated 2016-07-29
Summary
Dipeptidyl-peptidase-4 (DPP4) is an important regulator of incretins and inflammation, and participates in the pathophysiological process of acute myocardial infarction (AMI). However clinical data of DPP4a in AMI patients is sparse. This study was to investigate the role of plasma DPP4 activity (DPP4a) in patients with ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI). This was a analysis of consecutive patients conducted at a tertiary referral center from January 2014 to October 2015. The investigators included 747 STEMI-patients, treated with PCI from January 2013 to October 2015. Blood samples were collected immediately at admission. The patients were divided into four groups according to DPP4a quartile.
Conditions
- Dipeptidyl-peptidase-4
- STEMI
- PCI
- No-reflow
- Bleeding
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2015-10-31
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