Predictive Value Of Admission Blood Glucose Level In Patients With Acute Myocardial Infarction
NCT03164707 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2017-05-24
Summary
Coronary atherosclerosis is the leading cause of death worldwide. Diabetes mellitus is associated with increased prevalence of coronary artery disease
Increased plasma glucose is a common feature in the acute phase of myocardial infarction, even in patients without diabetes. Patients with stress hyperglycemia, but without previous diagnosis of diabetes, were at increased risk of congestive heart failure, arrhythmia and cardiogenic shock as well as increased both in-hospital and long-term mortality . Previous studies have demonstrated larger infarct size and poorer prognosis inpatients with hyperglycemia upon hospital admission compared with patients without hyperglycemia
It has been reported that stress hyperglycemia impairs microvascular circulation and may lead to no-reflow phenomenon. No reflow phenomenon was significantly more frequent among patients with hyperglycemia and increased progressively with increasing admission blood glucose in patients with Acute Myocardial Infarction . Furthermore, patients with high admission glucose are more likely to develop restenosis and require repeat revascularization procedures compared with those with normal admission glucose and are also at increased risk for repeated Myocardial Infarction, stent thrombosis and death.
Conditions
- Predictive Value of Admission Blood Glucose Level in Acute Myocardial Infarction
Interventions
- DIAGNOSTIC_TEST
-
Blood Glucose Level
ON Admission Blood Glucose Level Fasting Blood Glucose Level
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
George Motea Doos, M.B.B.CH · Assiut University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-12-01
- Primary Completion
- 2018-12-01
- Completion
- 2019-06-01
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