MedTrace Logo

NK Cell Activity in Smokers Screened for Lung Cancer

NCT02840578 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 242

Last updated 2018-05-11

No results posted yet for this study

Summary

Objectives: To examine whether NK cell activity associates with two confirmed risk factors: (1) presence of indeterminate lung nodule(s) and (2) smoking exposure after controlling for potential confounders, including age, gender, body mass index (BMI), personal history of any cancer, and family history of cancer. This project is aimed at measuring NK cell activity, which may eventually help in reducing false positive rates of LDCT screening, improve early detection of lung cancer, and assist in risk assessment in patients with lung cancer. The investigators hypothesize that measurement of NK cell activity may be a useful tool for assessing changes in immunosurveillance in patients with conditions or diseases where NK cell activity has been shown to be reduced, such as lung cancer

Conditions

Sponsors & Collaborators

  • ATGen Global

    collaborator UNKNOWN

  • University of Southern California

    lead OTHER

Principal Investigators

  • Christopher Lee, MD · University of Southern California

Eligibility

Min Age
50 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-16
Primary Completion
2018-03-05
Completion
2018-03-05

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02840578 on ClinicalTrials.gov