Benefit of Laparoscopic Adhesiolysis in Patients With Chronische Abdominal Pain

Summary

Laparoscopic adhesiolysis as a therapy for chronic pain is still controversial and long term effects are not known. The objective was to to evaluate long term effects of laparoscopic adhesiolysis for treating chronic abdominal pain.

Therefore one hundred patients with abdominal pain attributed to adhesions were randomized to laparoscopic adhesiolysis or a placebo group with laparoscopy alone. Pain relief was assessed after 3, 6 and 12 months and 12-year follow-up.

Conditions

• Chronic Pain
• Adhesions

Interventions

PROCEDURE

Laparoscopic adhesiolysis

After diagnostic laparoscopy to confirm adhesions and exclude other pathology laparoscopic adhesiolysis was performed

PROCEDURE

Diagnostic laparoscopy

After diagnostic laparoscopy to confirm adhesions and exclude other pathology treatment was stopped.

Sponsors & Collaborators

• Erasmus Medical Center

  collaborator OTHER

• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

  collaborator OTHER

• Rijnstate Hospital

  collaborator OTHER

• Maxima Medical Center

  collaborator OTHER

• Catharina Ziekenhuis Eindhoven

  collaborator OTHER

• Maasstad Hospital

  collaborator OTHER

• Isala

  collaborator OTHER

• Groene Hart Ziekenhuis

  lead OTHER

Principal Investigators

• Dingeman Swank, Dr · Groene Hart Ziekenhuis

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

1997-08-31

Primary Completion

2014-01-31

Completion

2014-01-31