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Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation

NCT02818270 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2017-02-01

No results posted yet for this study

Summary

Aerosol delivery through a ventilator is influenced by numerous factors from ventilator-related, circuit-related to device-related factors. Aerosolized drug delivery through a ventilator system was studied on bench model with albuterol, yet the results were often overestimated. The objective of this study was to evaluate inhaled bronchodilator and mucolytic agents delivered through a ventilator system.

Conditions

Interventions

DRUG

Salbutamol

Salbutamol (albuterol ) was delivered by a jet nebulizer with a 50 pis oxygen flow at 6 L/min.

DRUG

Acetylcysteine

Acetylcystine was delivered by a jet nebulizer with a 50 pis oxygen flow at 6 L/min.

Sponsors & Collaborators

  • Chang Gung Memorial Hospital

    collaborator OTHER

  • Chang Gung University

    lead OTHER

Principal Investigators

  • Hui-Ling Lin, MSc · Chang Gung University

Study Design

Allocation
NA
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2016-12-31
Completion
2016-12-31

Countries

  • Taiwan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02818270 on ClinicalTrials.gov