Peripheral Neuropathy

Disease

Disease Profile

Peripheral neuropathy is a disorder of peripheral nerves causing numbness, pain, tingling, weakness, and autonomic dysfunction, with etiologies including diabetes, toxins, infections, and immune conditions.

Category
neurological disorder
Prevalence
Peripheral neuropathy affects an estimated 20 million people in the United States.

Related News

Multiple Myeloma Treatment Landscape Evolves with T-Cell Therapies, Trial Design Challenges

The treatment landscape for multiple myeloma is evolving rapidly with T-cell engaging therapies like bispecific antibodies and CAR T-cell treatments shifting care toward a chronic condition with potential treatment breaks. This evolution is creating new side effect management challenges and complicating clinical trial design as sponsors grapple with selecting comparator arms and adapting to a rapidly shifting standard of care.

FDA Approves Lifyorli Plus Nab-Paclitaxel for Platinum-Resistant Ovarian Cancer

The FDA has approved Lifyorli (relacorilant) plus nab-paclitaxel for platinum-resistant ovarian cancer based on trial data showing improved survival. Separately, the agency granted Breakthrough Therapy designation to Lilly's sofetabart mipitecan for the same condition, expediting development of the antibody-drug conjugate.

Related Clinical Trials

NCT ID Title Status Phase
NCT07674420

Wearable Insoles for Recurrent Diabetic Ulcer Prevention

ACTIVE_NOT_RECRUITING NA
NCT07663396

Electroacupuncture for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Early-stage Cancer

NOT_YET_RECRUITING NA
NCT07662863

Sacituzumab Tirumotecan vs MMAE-ADCs in Advanced Urothelial Carcinoma (FUSCC-SPARE-UC-01)

NOT_YET_RECRUITING PHASE2
NCT07644533

Electroacupuncture for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Advanced Cancer

NOT_YET_RECRUITING NA
NCT07639060

Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain

RECRUITING
NCT07548476

Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

RECRUITING NA
NCT07501663

Optimizing Integrative Oncology Approaches to Address Chemotherapy-induced Peripheral Neuropathy in Gastrointestinal (GI) Cancer Patients: A SMART Pilot Study

RECRUITING NA
NCT07475065

The Effect of Oral DLBS1033 in Patients With Diabetic Polyneuropathy

NOT_YET_RECRUITING PHASE2/PHASE3
NCT07362147

Exploring the Effects of Hand and Foot Exercise Intervention in Older Adults With Gynecological Cancer Receiving Chemotherapy Improvement of Peripheral Neuropathy and Quality of Life

NOT_YET_RECRUITING NA
NCT07336381

Shortwave Diathermy In-home Treatment for Indianapolis VA-only Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy

NOT_YET_RECRUITING NA