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Inulin and S. Salivarius Reduce Halitosis

NCT02794766 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2020-08-19

Study results available
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Summary

Halitosis associated with tongue coating results from the production of volatile sulfur compounds by bacterial action. The use of prebiotics and probiotics might be useful in treating such condition. The aim of this study was to evaluate the effect of the prebiotic inulin combined with the probiotic Streptococcus salivarius (SS) on halitosis by coating.

Conditions

  • Halitosis
  • Tongue Diseases

Interventions

DRUG

Inulin+SS

Experimental treatment: A gum of inulin 1g plus Streptococcus salivarius 1 billion CFU per oral each 12 hours for 10 days

DRUG

S salivarius

Active comparator: A gum of Streptococcus salivarius 1 billion CFU per oral each 12 hours for 10 days

DRUG

Placebo

Placebo 1 gum each 12 hours for 10 days

Sponsors & Collaborators

  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

    collaborator OTHER_GOV

  • Universidade de Passo Fundo

    lead OTHER

Principal Investigators

  • Fernando Fornari · Universidade de Passo Fundo

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2015-05-31
Completion
2015-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02794766 on ClinicalTrials.gov