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Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study

NCT02780973 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2024-02-14

No results posted yet for this study

Summary

Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion.

Total protein concentration within the formed salivary pellicles on the bovine samples is determined. Further Salivary parameters (unstimulated and stimulated saliva flow rate, pH, buffer capacity, albumin and total protein content as well as concentration of inorganic calcium, phosphate and fluoride) are being measured.

The aim of this study is to investigate whether gender differences in the salivary composition correlate with predisposition to erosion.

Conditions

  • Dental Erosion

Interventions

OTHER

Wearing of an intraoral device with bovine tooth samples

Wearing of an intraoral device with bovine tooth samples

Sponsors & Collaborators

  • University of Göttingen

    lead OTHER

Principal Investigators

  • Annette Wiegand, Prof. Dr. med. dent. · Dept. of Prev. Dentistry, Periodontology and Cariology, University Medical Center Göttingen, Germany

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-07
Primary Completion
2018-01-18
Completion
2018-01-18

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02780973 on ClinicalTrials.gov