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Dentine Tubule Occlusion Assessment in a Modified in Situ Model

NCT02768194 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2018-06-25

Study results available
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Summary

This will be a single centre, single blind, randomized, three treatment, three period crossover design, modified, in situ, study in healthy participants. In this in situ model the tubule occlusion properties of dentifrices will be evaluated by comparing an experimental dentifrice formulation to a regular fluoride dentifrice and a negative control (mineral water) over a ten day period.

Conditions

  • Dentin Sensitivity

Interventions

DEVICE

Stannous fluoride

Dentifrice containing 0.454% stannous fluoride

OTHER

Sodium monofluorophosphate

Dentifrice containing 0.76% sodium monofluorophosphate

OTHER

Mineral water

Commercially available mineral water

Sponsors & Collaborators

Principal Investigators

  • GSK Clinical Trials · GlaxoSmithKline

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-06
Primary Completion
2016-09-01
Completion
2016-09-21

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02768194 on ClinicalTrials.gov