MedTrace Logo

A Randomized Trial Comparing Metered Dose Inhalers and Breath Actuated Nebulizers

NCT02777125 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 980

Last updated 2017-08-15

Study results available
· View outcomes & findings →

Summary

This study is determines if metered dose inhalers are as effective as breath actuated nebulizers for the treatment of mild to moderate asthma exacerbations in pediatric patients presenting to the emergency department. Half of the participating patients received albuterol via the metered dose inhaler whereas the other half received albuterol via the breath actuated nebulizer.

Conditions

Interventions

DEVICE

Metered Dose Inhaler

A metered dose inhaler (MDI) is a small hand held pressurized canister device that contains both a medication, in this case albuterol, and a propellant. Pressing the device delivers 90mcg of albuterol. The MDI is attached to a spacer device, which is a one way holding chamber which allows the medication to be delivered over a series of breaths.

DEVICE

Breath Actuated Nebulizer

The breath actuated nebulizer (BAN) device is a device that converts liquid medication, in this case albuterol, into an aerosol. It consists of a mouthpiece, a medication reservoir, and connective tubing that attaches to a compressor. This BAN device delivers medication when the patient takes a breath, but it can be attached to a mask and set to continuous nebulization for patients that are not able to coordinate their breaths.

Sponsors & Collaborators

  • University of Tennessee

    collaborator OTHER

  • Le Bonheur Children's Hospital

    lead OTHER

Principal Investigators

  • Mark A Snider, DO · University of Tennessee

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2015-04-30
Completion
2015-04-30

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02777125 on ClinicalTrials.gov