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Neuroinflammation and Cognitive Dysfunction After Orthopedic Surgery

NCT02759965 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2019-04-16

No results posted yet for this study

Summary

The primary hypothesis that orthopaedic surgery induces a neuroinflammatory response within 48 hours after elective hip or knee surgery and that there is an association between exaggerated CNS inflammatory response or impaired inflammatory resolution and postoperative cognitive dysfunction within one week and at three months postoperatively.

Conditions

  • Surgery
  • Acute Phase Reaction

Sponsors & Collaborators

  • Sahlgrenska University Hospital

    collaborator OTHER

  • Karolinska University Hospital

    lead OTHER

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-01
Primary Completion
2016-03-30
Completion
2018-12-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02759965 on ClinicalTrials.gov