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Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans

NCT02742467 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 702

Last updated 2021-08-24

No results posted yet for this study

Summary

The creole study is a A Multi-centre, multinational, randomised single-blind, parallel group, three-armed superiority trial which is aimed at comparing the efficacy of three "free" combinations of two anti-hypertensive agents on 24 hour ambulatory systolic blood pressure (ASBP) in black African hypertensive patients.

Conditions

Interventions

DRUG

Perindopril plus Amlodipine

Group 1

DRUG

Perindopril plus Hydrochlorothiazide

Group 2

DRUG

Amlodipine plus Hydrochlorothiazide

Group 3

Sponsors & Collaborators

  • Imperial College London

    collaborator OTHER

  • University of Cape Town

    collaborator OTHER

  • Hôpital Edouard Herriot

    collaborator OTHER

  • University of Nairobi

    collaborator OTHER

  • University College Hospital, Ibadan

    collaborator OTHER

  • Hospital General De Douala

    collaborator OTHER

  • Mulago Hospital, Uganda

    collaborator OTHER

  • University of Abuja

    lead OTHER

Principal Investigators

  • Neil Poulter, MD, MSc · Imperial College London

  • Bongani Mayosi, DPhil · University of Cape Town

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-07
Primary Completion
2018-06-01
Completion
2018-06-01

Countries

  • Nigeria

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02742467 on ClinicalTrials.gov