Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium
NCT02711670 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2023-04-27
Summary
Thiazide diuretics will be more effective in lowering urine calcium excretion if taken at night as compared to the daytime. It will therefore be more effective in reducing kidney stone recurrence in nephrolithiasis patients with elevated urine calcium who are known to have increased risk of kidney stones at night time.
Conditions
- Kidney Stones
Interventions
- DRUG
-
chlorthalidone
- DRUG
-
Hydrochlorothiazide
Sponsors & Collaborators
-
VA New York Harbor Healthcare System
lead FED
Principal Investigators
-
David Goldfarb, MD · New York Harbor VA Medical Center
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-02-28
- Primary Completion
- 2017-06-30
- Completion
- 2017-06-30
Countries
- United States
Study Locations
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