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Interaction Between a Calcimimetic Agent and the Renin Angiotensine Aldosterone System

NCT01519037 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2020-03-05

No results posted yet for this study

Summary

The aim of this study is to evaluate, in healthy volunteers, the acute modulating effect of cinacalcet on the RAAS, the effect of furosemide on parathyroid secretion of PTH and the interaction between furosemide and cinacalcet on parathyroid hormone secretion.

Conditions

  • Relationship Between Calcimimetic and the RAAS

Interventions

DRUG

Cinacalcet 60 MG

one dose of oral cinacalcet, 60mg

DRUG

Placebo oral tablet

one tablet of placebo

Sponsors & Collaborators

  • Swiss National Science Foundation

    collaborator OTHER

  • Centre Hospitalier Universitaire Vaudois

    lead OTHER

Principal Investigators

  • Michel Burnier, Professor · CHUV

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-06-30
Completion
2014-06-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01519037 on ClinicalTrials.gov