Perioperative Endothelial Dysfunction in Patients Undergoing Minor Abdominal Surgery
NCT02690233 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2018-01-31
Summary
This study on minor surgery serves to explore whether a dose-response relationship exists between surgical stress and endothelial dysfunction in the early postoperative period. The aim of this explorative and observational clinical study is to closely examine the endothelial function and its dynamics in the early postoperative period after minor surgery (lap. inguinal hernia repair). The endothelial function will be assessed indirectly by EndoPat and plasma biomarkers of nitric oxide bioavailability. The study will contribute to the understanding of perioperative myocardial injury, which is crucial for optimized treatment of patients at risk of cardiovascular complications.
Conditions
- Myocardial Injury
Interventions
- PROCEDURE
-
Elective Surgery
Elective laparoscopic inguinal hernia repair
Sponsors & Collaborators
-
Zealand University Hospital
lead OTHER
Principal Investigators
-
Sarah VE Busch, MD · Department of Surgery, Køge Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2017-01-31
- Completion
- 2017-06-30
Countries
- Denmark
Study Locations
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