MedTrace Logo

Mediation Analysis in Cardiac Surgery

NCT07092683 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 13683

Last updated 2026-01-05

No results posted yet for this study

Summary

This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery. Using mediation analysis methods, we aim to determine whether and to what extent intraoperative transfusion explains the association between preoperative anaemia and adverse postoperative outcomes. By elucidating this pathway, the study seeks to inform perioperative blood management strategies and support more personalized, risk-adapted approaches to minimize postoperative complications in anaemic patients undergoing cardiac procedures.

Conditions

  • Anemia
  • Cardiac Surgery
  • Transfusion
  • Mediation

Interventions

OTHER

anemia

preoperative anemia

OTHER

nonanemia

preoperative nonanemia

Sponsors & Collaborators

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2025-05-01
Completion
2025-05-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07092683 on ClinicalTrials.gov