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Peripheral and Mesenteric Perfusion in Elective Surgical Patients

NCT03395483 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-11-01

No results posted yet for this study

Summary

An important goal of haemodynamic monitoring and resuscitation is early detection of insufficient tissue perfusion and oxygenation. The mesenteric haemodynamic response to circulatory shock is complex, and diagnosis of bowel ischaemia poses significant difficulty. Assuming blood flow is diverted from the peripheral tissue and the gastrointestinal tract to vital organs, during circulatory shock, an objective, simple and non-invasive method of detecting peripheral tissue perfusion impairment might detect this at an early stage.

The peripheral perfusion index (PPI) reflects changes in peripheral perfusion and laser doppler flowmetry allows measurement of bowel tissue perfusion.

The aim of this study is to explore the association between changes in peripheral and intestinal perfusion in patients undergoing elective colorectal surgery exposed to intraoperative haemodynamic challenges.

Conditions

  • Peripheral Perfusion
  • Bowel Ischemia
  • Colorectal Surgery
  • Haemodynamic Instability

Interventions

OTHER

Haemodynamic monitoring

see Group description

Sponsors & Collaborators

  • Hvidovre University Hospital

    lead OTHER

Principal Investigators

  • Marianne Agerskov, MD, Research Fellow · Department af Anaesthesia, Hvidovre Hospital, University of Copenhagen

  • Jakob Højlund, Chief Physician · Department of Anaesthesia, Hvidovre Hospital, University of Copenhagen

  • Nicolai Bang Foss, Clinical Professor, DMSc. · Department of Anaesthesia, Hvidovre Hospital, University of Copenhagen

  • Henrik Sørensen, MD, DMSc. · Department of Anaesthesiology, Abdominal Centre, Rigshospitalet, University of Copenhagen

  • Niels Secher, Professor, DMSc. · Department of Anaesthesiology, Abdominal Centre, Rigshospitalet, University of Copenhagen

Eligibility

Min Age
18 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-10
Primary Completion
2019-10-01
Completion
2019-10-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03395483 on ClinicalTrials.gov