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NFKB1 and IKK Epsilon in Rheumatoid Arthritis

NCT02689115 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2016-02-23

No results posted yet for this study

Summary

Rheumatoid arthritis (RA) is a systemic and auto-immune disorder whose primary characteristic is the chronic inflammation of joints. The objective of this study was to evaluate whether there was an association between the NF-KB1/IKK epsilon genetic expression and the clinical activity in RA.

60 RA patients were included in the study, 30 with clinical activity and 30 with clinical remission The NF-KB1/IKK epsilon genetic expression was performed by real time quantitative Polymerase chain reaction (qPCR) through the Pfaffl method of relative quantification with Taqman probes.

Conditions

Interventions

OTHER

Genetic relative expression

The genetic expression of NF-KB1 and IKK epsilon were quantified in both groups.

Sponsors & Collaborators

  • Universidad Autonoma del Estado de Mexico

    collaborator OTHER

  • Asociación Científica Latina A.C.

    lead OTHER

Principal Investigators

  • Hugo Mendieta Zerón, PhD. · Asociación Científica Latina A.C.

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2014-06-30
Completion
2015-12-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02689115 on ClinicalTrials.gov