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Evaluation of the Intestinal Microbiota and Bacterial Translocation in Patients With Rheumatoid Arthritis

NCT01961310 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2025-11-21

No results posted yet for this study

Summary

The main objective of this study is to compare the intestinal microbiota in newly diagnosed rheumatoid arthritis (RA) with that from individuals without RA.

The first analysis will compare the proportion of filamentous bacteria in the intestinal microbiota between the two groups.

Conditions

  • Arthritis, Rheumatoid

Interventions

BIOLOGICAL

Plasma analysis for bacterial translocation

1 ml of plasma will be obtained (blood sample). DNA will be extracted and amplified, and real-time quantitative PCR (polymerase chain reaction) performed.

BIOLOGICAL

Stool analysis

DNA from stool samples will be extracted, amplified, and used to identify the bacteria species present.

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Nīmes

    lead OTHER

Principal Investigators

  • Catherine Dunyach-Rempy, PharmD, PhD · Centre Hospitalier Universitaire de Nîmes

  • Jean Philippe Lavigne, MD, PhD · Centre Hospitalier Universitaire de Nîmes

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-08
Primary Completion
2018-03-29
Completion
2018-03-29

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01961310 on ClinicalTrials.gov