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Microbial Dysbiosis in Rheumatoid Arthritis

NCT03802890 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2020-06-18

No results posted yet for this study

Summary

The MyRA study will primarily investigate whether there are associations between the structure and function of the gut microbiome and response to methotrexate in early rheumatoid arthritis patients. The microbiome will be characterised via shotgun metagenomic sequencing of microbial DNA present in stool samples taken during the participant's first 6 months of taking methotrexate.

Conditions

Sponsors & Collaborators

  • Action Arthritis

    collaborator OTHER

  • University of East Anglia

    collaborator OTHER

  • Norfolk and Norwich University Hospitals NHS Foundation Trust

    collaborator OTHER

  • Quadram Institute Bioscience

    lead OTHER

Principal Investigators

  • Simon Carding, Prof · Quadram Institute Bioscience

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2021-04-30
Completion
2021-07-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03802890 on ClinicalTrials.gov