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Target-controlled Infusion Model for Cefepime

NCT02688582 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2019-03-01

No results posted yet for this study

Summary

For this study, a previously developed population pharmacokinetic (popPK) model for cefepime (Jonckheere et al., submitted to JAC) was programmed in Rugloop vII, which is a software program to drive an infusion pump. By entering patient data (such as gender, serum creatinine, age and weight) in Rugloop II, a patient-specific dose will be calculated and given to the patient. This concept is known as Target Controlled Infusion (TCI). The aim of this study is to prospectively validate the popPK model using TCI.

Conditions

  • Antimicrobial Treatment

Interventions

OTHER

TCI group

Drug: cefepime, Device: Target Controlled Infusion pump connected to Rugloop vII software

Sponsors & Collaborators

  • University Ghent

    collaborator OTHER

  • University Medical Center Groningen

    collaborator OTHER

  • Onze Lieve Vrouw Hospital

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-01
Primary Completion
2018-03-01
Completion
2019-02-28

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02688582 on ClinicalTrials.gov