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DESIPHER_Speech Degradation as an Indicator of Physiological Degeneration in ALS

NCT02675075 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2020-08-18

Study results available
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Summary

A disease called Amyotrophic lateral sclerosis (or ALS), which leads to difficulty swallowing, breathing, and movement, has been found to be higher for those serving in the military than in the general population. There are approximately 4,200 Veterans with ALS and roughly 1,000 new cases each year. When doctors attempt to determine the degree to which an ALS patient is suffering from the disease, they apply tests that are "graded" by experts. However, this approach to testing patients may not be very accurate. Researchers aim to use a system called DESIPHER to "listen" to ALS patients and find speech mistakes related to their condition. Researchers believe that, by detecting different types of errors, DESIPHER serves as a new kind of indicator of medical problems such as difficulty breathing or swallowing, without human "grading". This may also lead to a better system for automatically understanding ALS patients' speech.

Conditions

Sponsors & Collaborators

  • Florida Institute for Human and Machine Cognition

    collaborator OTHER

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Samuel L. Phillips, PhD · James A. Haley Veterans' Hospital, Tampa, FL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-01
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02675075 on ClinicalTrials.gov