Swallowing Impairments in Adults With and Without Alzheimer's Disease
NCT06678100 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 240
Last updated 2026-05-08
Summary
This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involving the primary caregivers of individuals with Alzheimer's that are enrolled in the study to better understand the impact of swallowing impairments on the primary caregivers of those with Alzheimer's Disease.
Healthy adults and individuals with Alzheimer's disease will:
* undergo tests of cough and swallow function
* undergo tests of grip and tongue strength
* complete questionnaires
Caregivers of individuals with Alzheimer's disease will also complete questionnaires.
Conditions
- Alzheimer Disease
- Caregiver Burden
- Healthy Aging
- Dysphagia
Sponsors & Collaborators
-
Vanderbilt University Medical Center
lead OTHER
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-21
- Primary Completion
- 2027-02-28
- Completion
- 2028-02-29
Countries
- United States
Study Locations
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