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Hydration Status Assessment Through Body Composition Monitoring in Patients With Acute Myocardial Infarction

NCT02655341 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2016-01-14

No results posted yet for this study

Summary

Aims:

* evaluate the hydric status through bioimpedance spectroscopy in consecutive acute myocardial infarction patients referred for primary PCI;
* assessment of renal artery stenosis incidence through renal angiography in consecutive STEMI patients;
* fully characterize the complex hydration, metabolic and endothelial profile of these patients in the attempt to define the role played by dehydration in the complex dynamics of acute myocardial infarction.

Conditions

  • Dehydration
  • Acute Myocardial Infarction
  • Renal Artery Stenosis

Interventions

DEVICE

Body Composition Monitoring

using Fresenius device; two measurements before and after coronary intervention;

PROCEDURE

Coronarography

Preprocedural coronary arteriography is obtained after sterile preparation and draping of the patient, conscious sedation, infiltration of local anesthetic (lidocaine solution) at the femoral access site, placement of an arterial sheath in the femoral artery, and advancement of the renal guide catheter over a 0.035-in guidewire under fluoroscopic guidance. After the tip of the guide catheter is positioned at the ostium of the left coronary stem, an angiogram is obtained. After the guidewire is removed, the proximal end of the catheter is connected to a manifold, and 4-8 mL of contrast is manually injected during cineangiographic recording.

PROCEDURE

Primary Percutaneous Coronary Intervention

An intravenous antithrombotic agent, usually heparin, is administered before the clinician proceeds with angioplasty.

PROCEDURE

Renal Angiography

After the tip of the guide catheter is positioned at the ostium of the renal artery, an angiogram is obtained. After the guidewire is removed, the proximal end of the catheter is connected to a manifold, and 4-8 mL of contrast is manually injected during cineangiographic recording. This procedure is performed in the same time with primary PCI

Sponsors & Collaborators

  • Grigore T. Popa University of Medicine and Pharmacy

    lead OTHER

Principal Investigators

  • Adrian Covic, Professor · Grigore T. Popa University of Medicine and Pharmacy

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2017-01-31
Completion
2018-01-31

Countries

  • Romania

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02655341 on ClinicalTrials.gov