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Effect of PPCI on Diastolic Function & Levels of Galactin-3 in Patients With STEMI

NCT05107076 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2021-11-04

No results posted yet for this study

Summary

* 2D Echocardiography with color Doppler assessment: It will be done within 24 h after PPCI
* Peripheral blood samples were obtained within 48 hours after acute MI, and the serum will be frozen at -70°C until tested for Galactin-3 level.
* Follow up 2D Doppler echocardiography:

will be repeated at 40 days of the event.

Conditions

  • STEMI - ST Elevation Myocardial Infarction

Interventions

DIAGNOSTIC_TEST

2D Echocardiography with color Doppler assessment & Galactin-3 level in blood

* Measurements will be 1. Pulsed wave (PW) Doppler 2. E (early diastolic)/A (late diastolic) - Using PW Doppler 3. IVRT (isovolumic relaxation time) 4. Deceleration time (DT) - from the peak of E wave to baseline. 5. E/e'- PW tissue Doppler imaging (TDI) 6. Left atrial volume and left atrial volume index (LAVI) * Peripheral blood samples will be obtained within 48 hours after acute MI, and the serum will be frozen at -70°C until tested for Galactin-3 level.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Hatem Helmy, Professor · Assiut University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-30
Primary Completion
2023-01-31
Completion
2023-05-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05107076 on ClinicalTrials.gov