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Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives

NCT00679653 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 171

Last updated 2008-05-19

No results posted yet for this study

Summary

To study the effect of sibutramine treatment on weight reduction and blood pressure improvement in three groups with antihypertensive therapy whose blood pressure was not adequately controlled with antihypertensive combination treatment.

Conditions

Interventions

DRUG

sibutramine

8-wks, sibutramine, 10 mg, capsules, once daily

DRUG

sibutramine

8-wks, sibutramine, 15 mg, capsules, once daily

DRUG

verapamil/trandolapril

2 wk Run-in phase, antihypertensive therapy only

DRUG

metoprolol/HCT

2 wk Run-in phase, antihypertensive therapy only

DRUG

felodipine/ramipril

2 wk Run-in phase, antihypertensive therapy only

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-02-28
Primary Completion
2003-12-31

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00679653 on ClinicalTrials.gov