Role of Transcranial Direct Current Stimulation (tDCS) in Patients With Attention Deficit Hyperactivity Disorder (ADHD)

Summary

The purpose of this study is to determine whether transcranial direct current stimulation (tDCS) is effective in the treatment attention deficit hyperactivity disorder (ADHD).

Randomized, double-blind Controlled Clinical Trial

Subjects Adults (between 18 and 59 years of age) with ADHD who meet the inclusion criteria and who agree to participate in the study Will recruit from advertisements and clinical referrals to a PRODAH

Active tDCS Anode - right DLPFC Cathode - left DLPFC Electric current is 2mA - Current is applied for 20 min

Sham tDCS Same assembly is used Current is applied for 30 sec

Both groups 5 stimulation sessions on consecutive days

Following tools at Baseline, 1st week, 2 st week, 3st week and 4st week Adult ADHD Self-Report Scale (ASRS) SDS - Sheehan Disability Scale CGI - Clinical Global Impression

Conditions

• Attention Deficit Hyperactivity Disorder

Interventions

DEVICE

tDCS active

Stimulation will be performed with the anode placed over the right DLPFC, and the cathode placed on the left DLPFC. The applied electric current will be 2mA and is going to be applied for 20 minutes. The electrodes have a size of 35cm ² each and will be covered by sponges soaked with saline.

DEVICE

tDCS sham

For the sham tDCS, the same setting will be used. However, the current is going to be applied for only 30 seconds, not being able to induce effects on neuronal excitability.

Sponsors & Collaborators

• Federal University of Rio Grande do Sul

  collaborator OTHER

• Conselho Nacional de Desenvolvimento Científico e Tecnológico

  collaborator OTHER_GOV

• Hospital de Clinicas de Porto Alegre

  lead OTHER

Principal Investigators

• Pedro Schestatsky, MD, PhD · Professor of Department of Internal Medicine, UFRGS, Brazil.

• Douglas T Leffa, MD student · MD student from Federal University of Rio Grande do Sul (UFRGS), Brazil.

• Luis Augusto Rohde, MD, Phd · Professor of Department of Psychiatry, UFRGS, Brazil.

• Eugenio H Grevet, MD, phD · Associate Professor of Department of Psychiatry, UFRGS, Brazil.

• Carolina T Cachoeira, MD · Federal University of Rio Grande do Sul (UFRGS), Brazil

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-09-30

Primary Completion

2015-10-31

Completion

2015-10-31

Countries

• Brazil

Study Locations