Circadian Misalignment and Insulin Sensitivity
NCT02580513 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2017-06-09
Summary
This study will evaluate the effect of circadian misalignment on insulin sensitivity in healthy lean subjects in a randomized cross-over design. Subjects will be admitted to the research facility for two study periods of 3 and 3.5 days. In one of the study periods, the behavioral cycle will be shifted by 12 hours. Insulin sensitivity will be measured with a hyperinsulinemic euglycemic clamp.
Conditions
- Diabetes Mellitus, Type 2
- Insulin Resistance
Interventions
- BEHAVIORAL
-
Circadian Misalignment
Sponsors & Collaborators
-
Maastricht University Medical Center
lead OTHER
Principal Investigators
-
Patrick Schrauwen, PhD · Maastricht University Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2017-02-28
- Completion
- 2017-02-28
Countries
- Netherlands
Study Locations
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