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Training-induced Increased Left Ventricular Trabeculation

NCT02568072 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2021-08-05

Study results available
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Summary

This project will expand on research conducted by the investigators' group, where the investigators have demonstrated increased LV trabeculation, satisfying currently existing criteria for LV Non-Compaction Cardiomyopathy (LVNC), in groups exposed to high cardiac workloads. To the investigators' knowledge, this will be the first prospective study aiming to demonstrate a direct relationship between high levels of exercise and increased LV trabeculation. This study may add weight to the theory that this entity currently described as LVNC, is a morphological epiphenomenon common to many distinct myocardial remodeling processes associated with increased cardiac preload and afterload and may better define normal adaptive increases in LV trabeculation.

Conditions

  • Athletes Heart
  • Left Ventricular Hypertrabeculation

Sponsors & Collaborators

  • St. Bartholomew's Hospital

    collaborator OTHER

  • Cardiac Risk in the Young

    collaborator OTHER

  • British Heart Foundation

    collaborator OTHER

  • St George's, University of London

    lead OTHER

Principal Investigators

  • Sanjay Sharma, MD FRCP FESC · St George's, University of London

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2016-07-31
Completion
2016-07-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02568072 on ClinicalTrials.gov