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Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department

NCT02489630 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 116

Last updated 2021-03-12

Study results available
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Summary

This study investigates the use of low doses of ketamine, along with opiate pain medication, is more effective at controlling the acute pain of patients in the emergency department than opiate pain medication alone. In addition, this study examines whether patients treated with low doses of ketamine, along with opiate pain medication, will require less opiate pain medication to control their pain, and whether these patients are equally happy with their pain control as patients who receive only opiate pain medication.

Conditions

Interventions

DRUG

opiate analgesic

0.1mg/kg dose of morphine (or morphine equivalent) at 30 min time intervals based on patient pain score or more frequently upon request

DRUG

Ketamine

0.1mg/kg ketamine IV

DRUG

Normal Saline

1ml/kg normal saline placebo

Sponsors & Collaborators

  • Virginia Polytechnic Institute and State University

    collaborator OTHER

  • University of Memphis

    collaborator OTHER

  • Carilion Clinic

    lead OTHER

Principal Investigators

  • Corey R Heitz, MD · Physician

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2015-03-31
Completion
2015-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02489630 on ClinicalTrials.gov