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Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia

NCT03236805 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 285

Last updated 2022-12-21

No results posted yet for this study

Summary

This is a prospective, randomized, single-blind trial evaluating prehospital patients experiencing moderate to severe acute pain, defined as a numeric rating scale score greater than or equal to 5. Patients will be randomized to receive ketamine at or morphine by intravenous push.

Conditions

  • Pain Management

Interventions

DRUG

Ketamine

Initial bolus of 20 mg (around 0.3 mg per kg) followed by bolus of 10 mg every 5 minutes as reported by the recommandations of experts of the french society of urgency care

DRUG

Morphine

Bolus of 2 mg (patient with weight under 60 kgs) or bolus of 3 mg (patient with weight above 60 kgs) every 5 minutes as reported by the recommandations of experts of the french society of urgency care

Sponsors & Collaborators

  • Nantes University Hospital

    lead OTHER

Principal Investigators

  • Joel JENVRIN, Doctor · Nantes University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-23
Primary Completion
2022-11-26
Completion
2022-11-26

Countries

  • France

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03236805 on ClinicalTrials.gov