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Depression and Facial Identity Recognition Abilities in Patients With Multiple Sclerosis

NCT02468765 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38

Last updated 2025-09-04

No results posted yet for this study

Summary

Cognitive and emotional disorders are often encountered in multiple sclerosis (MS) cases: depressive and bipolar disorders are twice as frequent as in general population.

Cognitive disorders, (particularly attention and dysexecutive disorders), appear in early stages of the disease's evolution, in cases of lightly or moderately disabled patients, with a recent evolution, with a "minor" form of the disease, even in Clinically Isolated Syndromes (CIS). Emotional disturbances are essentially linked to mood disorders of depression-type.

Last ten years, emotional processing in multiple sclerosis cases was investigated in various trials, especially regarding the recognition of facial and emotional expressions. These studies reported data, supporting an impairment of the perception of emotion, particularly those with negative valence.

The objective of this study is to investigate the link between recognition of facial and emotional expressions and depression in multiple sclerosis cases.

Conditions

Interventions

OTHER

Neuropsychological and emotional evaluation with monitoring

Recognition tasks of emotional facial expressions with electroencephalogram, electrodermal activity measure and heart rate measure, questionnaires and neuropsychological tests

Sponsors & Collaborators

  • Lille Catholic University

    lead OTHER

Principal Investigators

  • Patrick Hautecoeur, MD · Groupment des Hôpitaux de l'Institut Catholique de Lille

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-04-24
Primary Completion
2016-05-30
Completion
2016-05-30

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02468765 on ClinicalTrials.gov