Traditional Three-incision Esophagectomy Versus Minimally Invasive Thorascopic and Laparoscopic Esophagectomy

Summary

Esophageal carcinoma is an aggressive malignancy with poor prognosis. Surgical resection remains the most effective method for this malignant disease. VATS esophagectomy has become more and more popular in China and around the world. Although VATS esophagectomy has been proven to be effective in preventing respiratory complications, there is still no ample evidences to demonstrate that VATS esophagectomy is as effective as traditional three-incision esophagectomy in lymph node dissection and is equal or superior in long-term survival. The purpose of this large scale prospective observational study is to compare the minimally invasive thorascopic/laparoscopic esophagectomy with traditional three-incision esophagectomy in lymph node dissection, postoperative recovery, postoperative complications, and long-term survival.

Conditions

• Esophageal Cancer

Interventions

PROCEDURE

open esophagectomy

PROCEDURE

Minimally invasive esophagectomy

Sponsors & Collaborators

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Henan Cancer Hospital

  collaborator OTHER_GOV

• Hebei Medical University Fourth Hospital

  collaborator OTHER

• Shanghai Zhongshan Hospital

  collaborator OTHER

• Harbin Medical University

  collaborator OTHER

• Sichuan Cancer Hospital and Research Institute

  collaborator OTHER

• Fujian Cancer Hospital

  collaborator OTHER_GOV

• Liaoning Cancer Hospital & Institute

  collaborator OTHER

• Hunan Cancer Hospital

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• Zhejiang Cancer Hospital

  collaborator OTHER

• Tang-Du Hospital

  collaborator OTHER

• Shanghai Chest Hospital

  collaborator OTHER

• Chinese Academy of Medical Sciences

  lead OTHER

Principal Investigators

• Jie He, MD,PhD · Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-01-31

Primary Completion

2017-12-31

Completion

2019-12-31

Countries

• China

Study Locations