Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction

Summary

The incidence of esophagogastric junction has been increasing in recent years, and surgery is an important method for the treatment of adenoma at the esophagogastric junction. Currently, there is a great controversy about the surgical method of Siewert II, mainly choosing the right chest or the left chest for thoracic surgery. Therefore, it is of great significance to further study the surgical methods of Siewert II esophagogastric junction adenoma. Objective: To compare the safety, feasibility, and clinical efficacy of endoscopic Ivor-Lewis versus laparoscopic extended abdominal gastrectomy for Siewert type Ⅱadenocarcinoma at the resectable esophagogastric junction.

Conditions

• Siewert Type II Adenocarcinoma of Esophagogastric Junction

Interventions

PROCEDURE

Endoscopy Ivor-lewis

Endoscopy Ivor-lewis

PROCEDURE

Laparoscopic transabdominal enlarged gastrectomy

Laparoscopic transabdominal enlarged gastrectomy

Sponsors & Collaborators

• Tang-Du Hospital

  collaborator OTHER

• Henan Provincial People's Hospital

  collaborator OTHER

• General Hospital of Ningxia Medical University

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• The First Affiliated Hospital of Shanxi Medical University

  collaborator OTHER

• Xijing Hospital of Digestive Diseases

  lead OTHER

Principal Investigators

• xiaohua li, MD,PH.D · Xijing Hospital

• xianli he, MD,PH.D · Tang-Du Hospital

• peichun sun, MD,PH.D · Henan Provincial People's Hospital

• lei wang, MD,PH.D · General Hospital of Ningxia Medical University

• xuejun sun, MD,PH.D · First Affiliated Hospital of Xi 'an Jiaotong University

• he huang, MD,PH.D · The First Affiliated Hospital of Shanxi Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-05-01

Primary Completion

2025-05-31

Completion

2028-05-31

Countries

• China

Study Locations