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Effect of Annona Muricata Leaves on Colorectal Cancer Patients and Colorectal Cancer Cells

NCT02439580 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2015-05-14

No results posted yet for this study

Summary

Annona muricata L., include the leaves, is found to contain biologically active Annonaceous acetogenins and plant polyphenols that are important components of human diet and a number of them are considered to have chemopreventive and therapeutic properties against cancer.

To confirm previous findings in in vitro, animal study and traditionally use, a human, ex vivo and in vitro studies were conducted to evaluate the effects of consecutive ingestion of A. muricata leaves extract for eight weeks.

Conditions

Interventions

DIETARY_SUPPLEMENT

Annona muricata extract

ethanol-soluble fraction of water extract

DIETARY_SUPPLEMENT

Placebo

maltose

Sponsors & Collaborators

  • Indonesia University

    lead OTHER

Principal Investigators

  • Lili Indrawati, MSc · Indonesia University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2014-06-30
Completion
2014-10-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02439580 on ClinicalTrials.gov