Venoarterial PCO2 Difference /Arteriovenous O2 Content Difference Ratio as Goal of Early Septic Shock Therapy
NCT01877798 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2013-06-14
Summary
Reducing tissue hypoxia is the ultimate goal of severe sepsis and septic shock therapy.Venoarterial PCO2 difference /arteriovenous O2 content difference ratio (△PCO2/Ca-vO2) is considered to be a good indicator of global anaerobic metabolism.The purpose of this study was to compare the efficacy of △PCO2/Ca-vO2 and central venous oxygen saturation (ScvO2) in the treatment of severe sepsis and septic shock.
Conditions
- Septic Shock
Interventions
- PROCEDURE
-
volume resuscitation, vasoactive drug
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-06-30
- Primary Completion
- 2016-06-30
Countries
- China
Study Locations
More Related Trials
-
CO2 Gap Changes in Septic Shock in Relation to Cardiac Output
NCT05578534 ·Status: COMPLETED
-
Ratio of ''Central Venous-to-Arterial Co2 Gap'' to ''Arterial-to-Central Venous O2 Content Gap'' in Septic Shock
NCT04425161 ·Status: UNKNOWN
-
Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring
NCT00407823 ·Status: COMPLETED ·Phase: NA
-
Role of PCO2 Gap as Predictor of Clinical Outcome in ICU Septic Patients
NCT06256198 ·Status: NOT_YET_RECRUITING
-
Venous to Arterial Carbon Dioxide Difference (P₍ᵥ-ₐ₎CO₂): Predictor of Septic Patient Prognosis Depending on the ScvO₂
NCT03292120 ·Status: COMPLETED ·Phase: NA
-
The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock
NCT03661268 ·Status: UNKNOWN ·Phase: NA
-
Microcirculatory Oxygen Uptake in Sepsis
NCT02430142 ·Status: COMPLETED
-
Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome
NCT01526382 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effect of Increasing the Mean Arterial Pressure on the Microcirculation and the Prognosis of Patients With Septic Shock
NCT04136080 ·Status: UNKNOWN ·Phase: NA
-
Protocol-driven Hemodynamic Support for Patients With Septic Shock
NCT00335907 ·Status: UNKNOWN ·Phase: NA
-
Comparison of ECMO Use and Conventional Treatment in Adults With Septic Shock
NCT01685112 ·Status: UNKNOWN
-
Microcirculation After MAP Increase in Septic Shock Patients With Previous Hypertension
NCT02519699 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Vasopressin and Other Pressors in Septic Shock
NCT00269685 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Comparison of a Tissue Perfusion Guided Hemodynamic Protocol With a Standard Hemodynamic Protocol in Septic Shock Patients
NCT01296789 ·Status: TERMINATED ·Phase: NA
-
Hemodynamic Effects of Vasopressin in Early Septic Shock Stage
NCT02053675 ·Status: COMPLETED ·Phase: NA
-
Observational Study About the Use of Perfusion Index to Use Vasopressor in Sepsis
NCT06860438 ·Status: RECRUITING
-
PiCCO ASSESSMENT IN PATIENTS WITH SEPTIC SHOCK
NCT05271032 ·Status: COMPLETED
-
The Construction and Application of Therapeutic System of Intelligent Decision-Oriented Hemodynamic Organized Therapy for Shock Patients
NCT05886192 ·Status: UNKNOWN ·Phase: PHASE4
-
VTE Incidence in Severe Sepsis and Septic Shock
NCT02353910 ·Status: COMPLETED
-
Effects of Terlipressin on Renal Perfusion in Patients With Septic Shock
NCT04948372 ·Status: COMPLETED ·Phase: NA
-
Hyperoxia and Hypertonic Saline in Septic Shock
NCT01722422 ·Status: TERMINATED ·Phase: NA
-
Pcrit and TPP for Risk Stratification in Patients with Sepsis
NCT06657196 ·Status: COMPLETED
-
ExtraCorporeal Membrane Oxygenation in the Therapy for REfractory Septic Shock With Cardiac Function Under Estimated
NCT05184296 ·Status: RECRUITING ·Phase: NA
-
Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation.
NCT05953142 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study
NCT02237833 ·Status: TERMINATED