MedTrace Logo

Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

NCT02387255 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 165

Last updated 2025-04-08

No results posted yet for this study

Summary

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.

Conditions

  • Abdominal Aortic Aneurysm

Interventions

DEVICE

Resoundant Driver System

This device is used to generate vibrations at the area of interest. The device has an active driver, a loud speaker sitting outside the scanner area, and a passive driver, which is shaped like a silicone paddle, which is secured with velcro straps to the area being imaged. Sound waves from the active driver travel through a tube attached to the passive driver and generate vibrations, images of which are captured by the MR scanner.

Sponsors & Collaborators

  • Ohio State University

    lead OTHER

Principal Investigators

  • Arunark Kolipaka, PhD · The Ohio State University Medical Center Dept. of Radiology

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2028-10-31
Completion
2028-10-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02387255 on ClinicalTrials.gov