Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis
NCT02344719 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2015-09-25
Summary
The investigators want to analyze the effect of Taurin on portal hemodynamics in patients with advanced liver cirrhosis.
Conditions
- Cirrhosis
- Portal Hypertension
Interventions
- DRUG
-
Taurin 6g per day per oral for 28 days
Taurin 6g per day per oral for 28 days
- PROCEDURE
-
HVPG Measurement baseline
On day 1 (baseline) and day 28 HVPG measurement will be performed
- PROCEDURE
-
HVPG Measurement day 28
On day 1 (baseline) and day 28 HVPG measurement will be performed
- DRUG
-
Placebo 6g per day per oral for 28 days
Placebo to Taurin 6g per day per oral for 28 days
Sponsors & Collaborators
-
Medical University of Vienna
lead OTHER
Principal Investigators
-
Arnulf Ferlitsch, MD · Medical University of Vienna
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-10-31
- Primary Completion
- 2015-05-31
- Completion
- 2015-06-30
Countries
- Austria
Study Locations
More Related Trials
-
Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis
NCT01331785 ·Status: WITHDRAWN ·Phase: NA
-
Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites
NCT00115947 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Albumin Infusion on Oxidative Albumin Modification, Albumin Binding Capacity and Plasma Thiol Status
NCT03214796 ·Status: COMPLETED
-
Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment
NCT03443934 ·Status: COMPLETED
-
Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding
NCT05624229 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Early TIPS in Patients With Liver Cirrhosis and Ascites
NCT06576934 ·Status: RECRUITING ·Phase: NA
-
Renal Function Determination in Patients With Liver Cirrhosis
NCT02047240 ·Status: COMPLETED
-
Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose
NCT04073290 ·Status: RECRUITING ·Phase: PHASE4
-
Surrogate Markers of Portal Pressure
NCT02508298 ·Status: COMPLETED ·Phase: NA
-
TIPS With or Without BCAA
NCT07281846 ·Status: RECRUITING ·Phase: NA
-
The Effect of Probiotics (VSL) on Portal Hypertension
NCT01032941 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Risk Factors and Outcomes of Acute Venous Thromboembolism in Cirrhotic
NCT03580577 ·Status: UNKNOWN
-
Portal Vein Thrombosis in Cirrhosis
NCT02275585 ·Status: WITHDRAWN
-
Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
NCT02335580 ·Status: COMPLETED
-
A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients
NCT02356250 ·Status: WITHDRAWN
-
Von Willebrand Factor Levels in Patients With Liver Cirrhosis and Portal Hypertension
NCT06694090 ·Status: NOT_YET_RECRUITING
-
The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy
NCT04221672 ·Status: UNKNOWN ·Phase: PHASE3
-
Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)
NCT01966419 ·Status: COMPLETED ·Phase: PHASE2
-
Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver Transplantation
NCT04472312 ·Status: COMPLETED
-
A Phase 1, Open-Label Study of Intravenous Sildenafil in Patients With Cirrhosis
NCT01954524 ·Status: TERMINATED ·Phase: PHASE1
-
Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome
NCT00742690 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis
NCT00344916 ·Status: COMPLETED ·Phase: PHASE1
-
Handgrip Strength Increases the Pressure in the Portal and Left Gastric Veins in Cirrhotic Patients
NCT07289698 ·Status: COMPLETED
-
Evaluation of the Role of Plasma Biomarkers in the Development of Decompensation in Patients With Cirrhosis .
NCT03084185 ·Status: UNKNOWN
-
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements
NCT04668664 ·Status: COMPLETED