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Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding

NCT05624229 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 672

Last updated 2023-09-28

No results posted yet for this study

Summary

Acute Variceal Bleeding (AVB) in patients with liver cirrhosis is a common clinical critical disease. There is little evidence for the effect of proton pump inhibitor (PPI) use in patients with AVB, and there is no study on the efficacy of PPI combined with standard therapy in patients with AVB.

Conditions

  • Upper Gastrointestinal Hemorrhage

Interventions

DRUG

Proton Pump Inhibitors

PPI infusion continued to use for 5 days in experimental group

DRUG

No Proton Pump Inhibitors

PPI infusion stopped in standard group after endoscopy.

Sponsors & Collaborators

  • West China Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2025-12-31
Completion
2028-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05624229 on ClinicalTrials.gov