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Coagulation in Cirrhosis

NCT05667805 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2025-01-14

No results posted yet for this study

Summary

Out of fear of bleeding, liver cirrhosis patients are often treated prophylactically with blood and coagulation products before minor interventions. The COUCH study will examine whether these patients benefit from a restrictive administration of coagulation products.

Conditions

Interventions

DRUG

Platelet Concentrate

Liberal use (standard treatment)

DRUG

Prothrombin Complex Concentrate

Liberal use (standard treatment)

OTHER

Restricitve Use

Restrictive use of human prothrombin complex and platelet concentrates. No prophylactic substitution.

Sponsors & Collaborators

  • Medical University of Vienna

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-19
Primary Completion
2027-01-01
Completion
2027-03-01

Countries

  • Austria

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05667805 on ClinicalTrials.gov