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Glutamate Probes in Adolescent Depression

NCT02307617 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 57

Last updated 2021-04-23

No results posted yet for this study

Summary

The purpose of this study is to learn if measures of brain chemicals from a brain scan called Magnetic Resonance Imaging and Spectroscopy (MRI/MRS) and brain activity (known as cortical excitability and inhibition) collected by Transcranial Magnetic Stimulation (TMS) are different in adolescents with depression who are in different stages of treatment.

Researchers are conducting this study to learn more about how the brain works in adolescents with depression and without depression (healthy controls). This is important because it may identify a biological marker (a measure of how bad an illness is) for depression that could one day be used to identify depressed adolescents who would benefit from certain treatments (medications for example) or to monitor how well treatments are working.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Paul E Croarkin, D.O. · Mayo Clinic

Eligibility

Min Age
13 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-08-01
Primary Completion
2017-04-17
Completion
2017-04-17

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02307617 on ClinicalTrials.gov