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QST-Pupillometry in Sickle Cell Disease Patients

NCT02242058 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2020-01-21

No results posted yet for this study

Summary

There has been little progress for effective treatment of pain in sickle cell disease (SCD) patients. Many organizations have recognized that understanding the causes and reducing the burden of pain in SCD is critical in order to improve the quality of life in SCD patients. As patients with SCD face the challenge of living with both acute and chronic pain which is often improperly treated, our translational and interdisciplinary project aims to identify objective measures of pain sensitivity and its biochemical and genetic correlates. We hypothesize that SCD patients will have decreased tolerance to thermal and electrical stimuli.

Conditions

  • SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)

Interventions

OTHER

Quantitative sensory testing

Sponsors & Collaborators

  • Julia Finkel

    lead OTHER

Principal Investigators

  • Julia Finkel, MD · Children's National Research Institute

Eligibility

Min Age
13 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2018-11-30
Completion
2018-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02242058 on ClinicalTrials.gov