EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)
NCT02240784 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 136
Last updated 2021-05-17
Summary
The purpose of this study is to characterize the natural history and clinical management of Acute Hepatic Porphyria (AHP) patients with recurring attacks.
Conditions
- Acute Hepatic Porphyria
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Medical Director · Alnylam Pharmaceuticals
Eligibility
- Min Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-08-31
- Primary Completion
- 2021-04-26
- Completion
- 2021-04-26
Countries
- United States
- Australia
- Belgium
- Bulgaria
- Czechia
- Finland
- France
- Germany
- Israel
- Italy
- Mexico
- Netherlands
- Norway
- Poland
- South Africa
- South Korea
- Spain
- Switzerland
- Taiwan
- United Kingdom
Study Locations
More Related Trials
-
Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris
NCT04658407 ·Status: UNKNOWN
-
Liver Disease in Patients With alpha1-antitrypsin Deficiency
NCT02929940 ·Status: UNKNOWN
-
A Multi-Center Trial to Study Acute Liver Failure in Adults
NCT00518440 ·Status: COMPLETED
-
Alpha-1 Antitrypsin Deficiency Adult Liver Study
NCT02014415 ·Status: ACTIVE_NOT_RECRUITING
-
Unknown Cause of Acute Liver Failure
NCT02041637 ·Status: COMPLETED
-
Pentoxifylline for Acute Alcoholic Hepatitis (AAH)
NCT00205049 ·Status: TERMINATED ·Phase: PHASE1
-
Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy
NCT04816916 ·Status: TERMINATED ·Phase: PHASE2
-
Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy
NCT05070351 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)
NCT04210245 ·Status: COMPLETED ·Phase: PHASE2
-
RAI & HRS: Relationship Between Relative Adrenal Insufficiency and Failure of Treatment in Hepatorenal Syndrome
NCT04273750 ·Status: COMPLETED
-
Hematological Disorders in EHPVO Patients
NCT07108023 ·Status: NOT_YET_RECRUITING
-
Inflammation, Immune Activation and Portal Hypertension in Alcoholic Hepatitis
NCT00992888 ·Status: COMPLETED ·Phase: NA
-
A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems
NCT06512454 ·Status: RECRUITING
-
A Multi-Center Group to Study Acute Liver Failure in Children
NCT00986648 ·Status: COMPLETED
-
Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC
NCT07132515 ·Status: RECRUITING ·Phase: PHASE4
-
Characterization of Metabolomic Fingerprints in Patients With Acute Liver Failure and Acute-on-chronic Liver Failure With Hepatic Encephalopathy
NCT05772585 ·Status: WITHDRAWN
-
Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis
NCT06855056 ·Status: RECRUITING
-
Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection
NCT05304455 ·Status: COMPLETED ·Phase: NA
-
Recurrence of Acute Alcoholic Pancreatitis
NCT00523874 ·Status: COMPLETED
-
N-Acetylcysteine in Severe Acute Alcoholic Hepatitis
NCT00962442 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)
NCT01966419 ·Status: COMPLETED ·Phase: PHASE2
-
Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1
NCT02770716 ·Status: COMPLETED ·Phase: PHASE3
-
To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.
NCT06066814 ·Status: UNKNOWN
-
Prevalence of Liver Disease in Patients Dependent on Parenteral Nutrition
NCT05011370 ·Status: COMPLETED
-
International Alfapump Cohort Study
NCT04326946 ·Status: ACTIVE_NOT_RECRUITING