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Hematological Disorders in EHPVO Patients

NCT07108023 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 115

Last updated 2025-08-06

No results posted yet for this study

Summary

This study focuses on patients who have a condition called extrahepatic portal vein obstruction (EHPVO), where a blood clot blocks the portal vein outside the liver. This blockage can cause problems like an enlarged spleen, bleeding from swollen veins in the digestive system, and low blood cell counts. Many of these patients may have hidden blood disorders that increase the risk of clotting, such as myeloproliferative neoplasms (MPNs), antiphospholipid syndrome (APS), or paroxysmal nocturnal hemoglobinuria (PNH). This study will collect and analyze blood test results-such as complete blood count (CBC), liver function tests (LFTs), and clotting tests-from patients with EHPVO. The aim is to find patterns that may suggest an underlying blood disorder, even if the patient doesn't show obvious symptoms.By understanding these patterns early, doctors may be able to diagnose and treat the root causes of clotting in these patients more accurately, helping prevent complications and improve outcomes.

Conditions

  • Extrahepatic Portal Vein Obstruction (EHPVO)
  • Thrombophilia
  • Myeloproliferative Neoplasms (MPN)
  • Antiphospholipid Syndrome (APS)
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Thrombocytopenia
  • Anemia
  • Leukopenia

Interventions

OTHER

No intervention (Observational Study)

This is a retrospective observational study with no assigned intervention. Data will be collected from patient medical records only

Sponsors & Collaborators

  • Rahab Nady

    lead OTHER

Principal Investigators

  • Mohamed Q Professor of internal medicine · Assiut University

  • Maha M Dr Maha Mohamed Abdelaziz, Dr at Internal medicine · Assiut University

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-31
Primary Completion
2025-12-31
Completion
2025-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07108023 on ClinicalTrials.gov