Integrative Epidemiology of Prognosis in Patients With Acute Alcoholic Hepatitis at AP-HP
NCT07262515 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1400
Last updated 2025-12-03
Summary
Acute alcoholic hepatitis (AAH) is a severe liver disease that often occurs in individuals with prolonged excessive alcohol consumption. Patients face a high risk of liver failure, complications, and death, despite available treatments. Current prognostic scores based on blood tests provide limited accuracy and do not capture the full complexity of the disease.
The purpose of this study is to improve the prediction of patient outcomes after a diagnosis of acute alcoholic hepatitis. By integrating clinical, biological, and histological information collected from the AP-HP data warehouse, the investigators aim to identify more reliable prognostic markers. This could help physicians better tailor treatments and improve survival of patients affected by this condition.
Conditions
- Acute Alcoholic Hepatitis
Sponsors & Collaborators
-
URC-CIC Paris Descartes Necker Cochin
collaborator OTHER -
Ministry of Health, France
collaborator OTHER_GOV -
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Vincent MALLET · Assistance Publique - Hôpitaux de Paris
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-07-19
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- France
Study Locations
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