A Multi-Center Group to Study Acute Liver Failure in Children
NCT00986648 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 158
Last updated 2016-01-12
Summary
The PALF study group began with 20 sites and now continues with 12 sites (11 in the United States and 1 in Canada) in the new funding period. The primary objective of the Pediatric Acute Liver Failure (PALF) study is to collect, maintain, analyze, and report clinical, epidemiological, and outcome data in children with ALF, including information derived from biospecimens.
Conditions
- Acute Liver Failure
- Hepatic Encephalopathy
Sponsors & Collaborators
-
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
collaborator NIH -
University of Pittsburgh
lead OTHER
Principal Investigators
-
Robert H Squires, MD · Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh
Eligibility
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-01-31
- Primary Completion
- 2015-12-31
- Completion
- 2015-12-31
Countries
- United States
- Canada
- United Kingdom
Study Locations
More Related Trials
-
A Retrospective Multicenter Study of HBV-related Pre-acute-on-chronic Liver Failure in China
NCT03281265 ·Status: COMPLETED
-
Chronic Liver Disease in Urea Cycle Disorders
NCT03721367 ·Status: COMPLETED
-
Study of N-Acetylcysteine in Acute Liver Failure (ALF)
NCT00896025 ·Status: TERMINATED ·Phase: PHASE4
-
Characterization of Metabolomic Fingerprints in Patients With Acute Liver Failure and Acute-on-chronic Liver Failure With Hepatic Encephalopathy
NCT05772585 ·Status: WITHDRAWN
-
Unknown Cause of Acute Liver Failure
NCT02041637 ·Status: COMPLETED
-
Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis
NCT05181332 ·Status: UNKNOWN
-
Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver Failure
NCT05566548 ·Status: UNKNOWN
-
Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris
NCT04658407 ·Status: UNKNOWN
-
To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
NCT02465619 ·Status: WITHDRAWN
-
Standard Volume vs. High Volume Plasma Exchange in Pediatric Acute Liver Failure
NCT06831643 ·Status: RECRUITING ·Phase: NA
-
Causes, Complications and Outcomes of Severe Acute Liver Disease Cases Admitted to Intensive Care Units
NCT05879445 ·Status: UNKNOWN
-
Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure
NCT02965560 ·Status: COMPLETED
-
Prognostic Significance of Acute Change in Liver and Splenic Stiffness in Patients of Acute on Chronic Liver Failure
NCT06069284 ·Status: UNKNOWN
-
LiverPAL: A Pilot Study of Inpatient Palliative Care for Patients With Advanced Liver Disease
NCT04953143 ·Status: COMPLETED ·Phase: NA
-
Prognosis of Patients With Acute-on-chronic Liver Failure
NCT05393453 ·Status: UNKNOWN
-
Acute on Chronic Liver Failure in Cirrhotic Patients at Assiut University Hospitals
NCT06142968 ·Status: NOT_YET_RECRUITING
-
Platelet Transfusion in Acute-on Chronic Liver Failure
NCT04564651 ·Status: UNKNOWN ·Phase: NA
-
Liver Disease in Urea Cycle Disorders
NCT04612764 ·Status: ACTIVE_NOT_RECRUITING
-
High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.
NCT03115697 ·Status: WITHDRAWN ·Phase: NA
-
To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.
NCT06066814 ·Status: UNKNOWN
-
Biomarkers in Liver Failure
NCT02833064 ·Status: ACTIVE_NOT_RECRUITING
-
Stratification of Chronic Alcoholic Liver Diseases (SCALE Study)
NCT03295812 ·Status: UNKNOWN
-
Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury
NCT01548690 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.
NCT05778461 ·Status: UNKNOWN ·Phase: NA
-
High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure
NCT02719210 ·Status: COMPLETED ·Phase: NA